Inflammation and wound diabetic
نویسندگان
چکیده
منابع مشابه
Notch Regulates Macrophage-Mediated Inflammation in Diabetic Wound Healing
Macrophages are essential immune cells necessary for regulated inflammation during wound healing. Recent studies have identified that Notch plays a role in macrophage-mediated inflammation. Thus, we investigated the role of Notch signaling on wound macrophage phenotype and function during normal and diabetic wound healing. We found that Notch receptor and ligand expression are dynamic in wound ...
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OBJECTIVE Inflammation is both central to proper wound healing and a key driver of chronic tissue injury via a positive-feedback loop incited by incidental cell damage. We seek to derive actionable insights into the role of inflammation in wound healing in order to improve outcomes for individual patients. APPROACH To date, dynamic computational models have been used to study the time evoluti...
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OBJECTIVE Subclinical inflammation represents a risk factor of type 2 diabetes and several diabetes complications, but data on diabetic neuropathies are scarce. Therefore, we investigated whether circulating concentrations of acute-phase proteins, cytokines, and chemokines differ among diabetic patients with or without diabetic polyneuropathy. RESEARCH DESIGN AND METHODS We measured 10 marker...
متن کاملDiabetic neuropathic foot ulcers: the association of wound size, wound duration, and wound grade on healing.
OBJECTIVE The goal of this study was to evaluate whether simple risk factors can be identified that successfully characterize who will heal and who will not heal among patients who have received standard therapy for diabetic neuropathic foot ulcers. RESEARCH DESIGN AND METHODS For this cohort study, we evaluated >31,000 individuals with a diabetic neuropathic foot ulcer seen in the Curative H...
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ژورنال
عنوان ژورنال: Jurnal Kedokteran dan Kesehatan Indonesia
سال: 2016
ISSN: 2085-4145,2527-2950
DOI: 10.20885/jkki.vol7.iss3.art1